eTwo™ combines the unique Sublime and Sublative applications for comprehensive facial rejuvenation

eTwo™’s applications provide for a wide range of both fine and deep wrinkle treatments; effective in improving skin texture, tone, laxity, acne scars, stretch marks or striae; as well as treatment for other skin scars.

  • Sublative™ for skin rejuvenation, uses fractionated bi-polar radio frequency technology places the heat energy effectively into the upper dermis where it can produce a significant increase in both collagen and elastin with minimal epidermal disruption.

  • Sublime™ for skin firming, uses the well-known and proven elōs technology, a combination of predictable and effective levels of infrared light and bi-polar radio frequency energies to remodel the deep dermal layer of the skin by stimulating new collagen growth.


Book your consultation with Panakeia (UK).


How does Sublative™ work?

The ergonomic Sublative™ applicator delivers bipolar radiofrequency energy via a matrix of electrodes in the disposable applicator tip. This fractional delivery of RF energy causes micro epidermal ablative injuries with wider spread dermal injury. This initiates a strong wound healing response in the dermal matrix while also minimizing the damage to the epidermis. Less affected tissue surrounding the matrix points may be stimulated by heat which helps accelerate the healing process, leading to a smoother, rejuvenated appearance of the skin. Mild to moderate wrinkles and superficial skin discolouration are reduced, and skin texture becomes more smooth and elastic.

+ Can all areas be treated?

The Sublative RF applicator comes with multiple tip configurations for various treatment protocols – 64 pin tips for fast full face improved skin tone and texture, as well as the 44 pin tip for smaller areas and focused treatments of under-eye laxity, wrinkles around the mouth and forehead wrinkles.

+Who should be treated with Sublative™?

Treatment is a proven and effective solution for all skin types.

+When can patients expect to see results?

Immediately post-treatment, they may notice tone and texture improvements as a result of increased levels of beneficial collagen and new healthy skin cells which are produced. With the treatment’s dermal impact, mild to moderate wrinkles and superficial skin discolouration is reduced.

Typically 3 – 5 treatments, 4 – 6 weeks apart. The total number of required treatment sessions depends on the skin condition of the patient.

+ How is the Sublative™ treatment tolerated by patients?

During treatment, many patients feel a warm, prickly sensation. After treatment a pink or “sunburn” appearance and feeling is common. Topical anaesthetic and cooling are often used to reduce discomfort during treatment.

+ Is there downtime?

There is minimal downtime with a maximum expected downtime of 2 or 3 days. Most patients can quickly resume their normal activities immediately post treatment.

How does Sublime™ work?

Sublime uses the proven elōs combination of predictable and effective levels of infrared light and bipolar radiofrequency energies to provide controlled deep dermal heating which remodels the dermal layer of the skin by stimulating new collagen growth. This predictable heating of the deep dermis both shrinks aged collagen fibres and stimulates new collagen synthesis, resulting in the immediate and long-term improvement of wrinkles and facial contour with a very low risk of side effects and virtually no downtime.


+What results can one expect from the Sublime™ treatment?

Sublime™ can improve sagginess of the face, neck and some body areas such as the abdomen or upper arms. Skin texture can also be smoothed out by the firming effect of treatment. This treatment is performed non-ablatively, which means this is a non-invasive procedure. Most people leave the treatment office with only slight pinkness or no pinkness at all.

+Does it hurt?

Sublime™ is a gentle, comfortable treatment requiring virtually no downtime. Most patients return to normal activities immediately after the treatment. Cooling of the skin’s surface provides enhanced safety and additional comfort.

+How often are treatments done?

Typically between 3 – 5 sessions approximately 4 weeks apart. The best results are seen 3 – 6 months post completion with maintenance approximately every 6 months.

+When can the patient expect to see results?

Most patients see immediate and cumulative results throughout the Sublime™ treatments. The total number of required treatment sessions depends on the patient’s skin condition.

+How is the Sublime™ treatment tolerated by patient?

Sublime™ is well tolerated by most patients without any topical anaesthetic or other means of pain relief. The treatment tip is chilled so it provides contact cooling to the skin surface for added comfort.

+Who should be treated with Sublime™?

Sublime™ is suitable to treat all skin types for sagginess, loss of elasticity, or textural irregularities. Treatment can be done on the face, neck, or other areas of the body.

+ eTwo Pricing

Sublative™ Treatment:
Full face (Single Treatment):
£275 per session
Eye and mouth area (Single Treatment:) £125 per session
Body Treatments: Prices will be confirmed during/after Consultation
Sublime™ Treatment (Single Treatment) £150 per treatment
Combined Sublime™ and Sublation™ (Single Treatment:) £400 per treatment
All prices shown are guide prices and will be confirmed after consultation.