Pigmentary disorders can be psychologically devastating. Cyspera Cysteamine 7% has become the first-line treatment, free of hydroquinone.
Hydroquinone has been used for decades as the gold standard for stubborn discolouration concerns. Although still controversial, hydroquinone has a reputation as a mutagenic and carcinogenic compound. It is a melano- cytotoxic agent that is known to induce ochronosis. Non-hydroquinone compounds such as kojic acid, arbutin, azelaic acid, retinoids, hydroxy acids show lower efficacy.